Published studies and research papers related to the discovery and application of Exscien’s fusion protein to various disease states

Our world-class research affiliations continues to advance the applications of this platform technology with research partners in the United States, Canada and Europe. The full development of this technology will yield first-in-class therapies directed at protecting, as well as repairing, cellular damage wherever oxidative stress plays a role. The following are references related to the discovery and application of Exscien’s fusion protein.

General
Cardiovascular
  • Bradley JM, Otsuka H, Bhushan S, Islam KN, Ziblich CM, Organ CL, Polhemus DJ, Wilson GL, Lefer DJ. A Novel Mitochondrial DNA Repair Enzyme Attenuates Maladaptive Remodeling and Preserves Cardiac Function in Heart Failure (submitted to JACC)
Stroke Reperfusion
Breast Cancer
Lung injury
Organs for transplantation
Macular degeneration
Other age related visual losses
  • Lin JB, Tsubota K, Apte RS. A glimpse at the aging eye. Aging and Mechanisms of Disease,2 doi:10.1038/npjamd.2016.3
Diabetes
Alzheimer’s Disease
Parkinson’s Disease
Inflammatory Bowel Disease (Crohn’s disease and Ulcerative Colitis)